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 Data Table 4

 Clinical Research Studies

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Note: All values are from data submitted annually by Centers starting from 2010 to recent year.

The following table compares the number of open trials and number of patients accrued to open trials for all NCI-designated Cancer Centers combined.

Number of Trials and Patients Accrued categozied by Fiscal Year and Study Source
FY Study Source Open Trials Patient Accrued
FY Total Number Median Total Number Median
2016 Industry 7,544 106 26,580 323
2016 External Peer Reviewed 2,330 35 105,486 600
2016 Institutional 7,375 93 195,477 1,378
2016 National Cooperative Group 5,796 95 13,416 165
2016 Other/Unknown 705 11 198,686 18
2015 Industry 6,847 100 24,778 270
2015 External Peer Reviewed 2,597 32 124,701 607
2015 Institutional 7,247 89 219,539 1,758
2015 National Cooperative Group 6,037 101 15,957 183
2015 Other/Unknown 600 1 194,420 0
2014 Industry 6,078 89 124,795 210
2014 External Peer Reviewed 2,606 35 140,560 766
2014 Institutional 7,123 85 540,506 1,877
2014 National Cooperative Group 6,536 102 23,951 180
2014 Other/Unknown 563 1 44,846 1
2013 Industry 1,114 72 5,626 278
2013 External Peer Reviewed 403 34 13,283 313
2013 Institutional 2,094 49 44,666 722
2013 National Cooperative Group 648 71 1,872 66
2013 Other/Unknown 20,072 314 909,966 1,535
2012 Industry 5,027 76 20,611 207
2012 External Peer Reviewed 2,581 36 85,077 360
2012 Institutional 6,500 70 161,280 781
2012 National Cooperative Group 7,126 122 17,289 181
2012 Other/Unknown 3,571 93 106,377 2,135
2011 Industry 5,489 86 21,340 160
2011 External Peer Reviewed 2,669 31 67,229 134
2011 Institutional 6,941 79 134,534 828
2011 National Cooperative Group 8,028 123 16,419 174
2011 Other/Unknown 1,795 39 54,301 349
2010 Industry 5,467 80 18,299 193
2010 External Peer Reviewed 2,470 26 80,663 204
2010 Institutional 6,179 58 126,171 713
2010 National Cooperative Group 7,709 115 18,903 262
2010 Other/Unknown 2,129 0 174,449 0
FY FY Total Total of Open Trials Total of Accrued Patients

It is important to note that these are not necessarily unique trials; the same trial may be open at multiple centers.


Number of Trials and Patients Accrued by Clinical Research Category categorized by Fiscal Year and Clinical Research Category
FY Research Category Open Trials Patient Accrued
FY Total Number Median Total Number Median
2016 INT 17,635 256 104,869 1,199
2016 OBS 3,177 46 362,410 735
2016 ANC/COR 2,925 33 72,275 510
2016 N/A 13 1 91 0
2015 INT 17,156 250 111,521 1,105
2015 OBS 3,175 41 389,559 1,200
2015 ANC/COR 2,863 33 78,154 612
2015 N/A 134 1 161 0
2014 INT 16,849 234 121,727 937
2014 OBS 3,121 43 661,321 1,397
2014 ANC/COR 2,932 34 91,604 740
2014 N/A 4 1 6 3
2013 Agent/Device 2,735 198 15,372 535
2013 Anc/Comp/Cor 706 33 10,970 574
2013 Epi/Obs/Out 1,065 49 48,513 1,546
2013 Other Intervention 447 21 15,738 1,077
2013 Unspecified 18,193 351 822,945 4,228
2012 Agent/Device 14,435 213 52,607 557
2012 Anc/Comp/Cor 3,448 43 85,991 961
2012 Epi/Obs/Out 3,330 42 156,310 1,336
2012 Other Intervention 1,048 16 25,462 301
2012 Unspecified 2,544 204 70,264 3,064
2011 Agent/Device 15,552 231 45,433 544
2011 Anc/Comp/Cor 4,179 45 78,119 514
2011 Epi/Obs/Out 3,778 41 140,861 929
2011 Other Intervention 1,384 14 29,128 122
2011 Unspecified 29 14 281 141
2010 Agent/Device 15,348 231 53,959 670
2010 Anc/Comp/Cor 3,666 40 75,848 577
2010 Epi/Obs/Out 3,609 33 247,778 1,160
2010 Other Intervention 1,299 13 40,710 101
2010 Unspecified 32 0 190 0
FY FY Total Total of Open Trials Total of Accrued Patients

It is important to note that these are not necessarily unique trials; the same trial may be open at multiple centers.

Number of Trials and Patients Accrued categorized by Fiscal Year and Phase
FY Phase Open Trials Patient Accrued
FY Total Number Median Total Number Median
2016 0 79 2 680 30
2016 I 3,098 42 10,976 104
2016 I/II 1,654 22 6,245 69
2016 II 5,731 85 22,037 215
2016 II/III 444 7 959 9
2016 III 4,549 72 17,072 177
2016 III/IV 12 1 270 11
2016 IV 128 2 720 5
2016 IV/V 1 1 29 29
2016 Pilot/Feasibility 1,456 22 16,157 144
2016 N/A 6,598 84 464,500 2,116
2015 0 44 5 199 13
2015 I 2,940 41 11,299 104
2015 I/II 1,466 18 5,869 56
2015 II 5,460 76 21,265 174
2015 II/III 390 7 974 8
2015 III 4,668 74 19,122 186
2015 III/IV 6 1 203 11
2015 IV 126 2 878 5
2015 Pilot/Feasibility 1,498 20 16,556 134
2015 N/A 6,730 87 503,030 2,481
2014 0 21 2 105 3
2014 I 2,762 36 12,212 35
2014 I/II 1,373 18 7,086 22
2014 II 5,435 73 22,521 94
2014 II/III 262 4 989 0
2014 III 4,880 79 19,232 100
2014 III/IV 3 1 200 100
2014 IV 105 2 476 0
2014 IV/V 1 1 0 0
2014 Pilot/Feasibility 1,413 19 72,868 31
2014 N/A 6,651 90 738,969 1,034
2013 0 11 1 48 3
2013 I 2,773 35 12,762 101
2013 I/II 1,100 14 4,131 41
2013 II 5,770 79 20,265 193
2013 II/III 207 4 606 4
2013 III 5,090 79 15,203 171
2013 III/IV 6 2 237 0
2013 IV 78 2 382 5
2013 IV/V 2 1 4 2
2013 V 5 5 8 8
2013 Pilot/Feasibility 1,335 20 17,343 129
2013 N/A 7,696 86 918,479 2,852
2012 0 4 1 15 2
2012 I 2,741 38 11,845 97
2012 I/II 1,057 14 4,380 30
2012 II 5,558 75 26,504 217
2012 II/III 280 3 1,070 3
2012 III 5,292 87 15,259 153
2012 III/IV 6 1 52 0
2012 IV 84 2 430 4
2012 IV/V 1 1 8 8
2012 V 4 4 13 13
2012 Pilot/Feasibility 1,270 20 16,957 119
2012 N/A 8,508 99 314,101 2,871
2011 I 2,731 40 10,266 67
2011 I/II 1,131 16 3,628 34
2011 II 5,530 77 21,657 180
2011 II/III 123 3 246 1
2011 III 5,271 92 12,000 150
2011 III/IV 3 1 10 3
2011 IV 85 2 305 1
2011 IV/V 2 2 2 2
2011 Pilot/Feasibility 1,284 17 29,589 112
2011 N/A 8,760 99 216,121 1,835
2011 I/III 2 2 0 0
2010 0 2 0 21 0
2010 I 2,526 40 14,321 97
2010 I/II 1,139 14 4,040 38
2010 II 5,663 88 20,540 204
2010 II/III 118 1 399 1
2010 III 5,093 85 17,652 209
2010 III/IV 8 0 48 0
2010 IV 92 1 576 1
2010 IV/V 1 0 3 0
2010 V 2 0 2 0
2010 Pilot/Feasibility 1,286 17 14,010 90
2010 N/A 8,024 95 346,873 3,193
FY FY Total Total of Open Trials Total of Accrued Patients

It is important to note that these are not necessarily unique trials; the same trial may be open at multiple centers.

Number of Trials and Patients Accrued categorize by Fiscal Year and Primary Purpose
FY Primary Purpose Open Trials Patient Accrued
FY Total Number Median Total Number Median
2016 BAS 2,412 25 65,147 421
2016 DIA 823 10 12,076 110
2016 HSR 358 4 202,673 59
2016 PRE 439 6 28,132 90
2016 SCR 307 4 16,045 106
2016 SUP 1,051 15 14,287 134
2016 TRE 15,558 236 51,242 595
2016 OTH 2,802 40 150,043 650
2015 BAS 2,287 21 68,785 314
2015 DIA 783 8 10,908 75
2015 HSR 304 3 202,870 64
2015 PRE 480 5 28,982 55
2015 SCR 301 4 18,762 48
2015 SUP 1,035 14 13,961 125
2015 TRE 15,013 219 51,445 526
2015 OTH 3,125 38 183,682 850
2014 BAS 2,511 23 89,750 463
2014 DIA 765 8 15,168 84
2014 HSR 228 3 96,200 35
2014 PRE 423 4 20,501 50
2014 SCR 247 4 22,226 139
2014 SUP 1,003 12 16,789 109
2014 TRE 14,778 205 53,566 506
2014 OTH 2,951 38 560,458 862
2013 Anc/Comp/Cor 176 30 3,925 289
2013 Epi/Obs/Out 295 44 18,527 963
2013 Pre 45 9 1,082 38
2013 Scr/Det/Dia 166 10 7,411 566
2013 Sup/QoL 98 7 2,095 150
2013 The 1,591 185 5,846 409
2013 N/A 21,710 327 948,455 1,363
2012 Anc/Comp/Cor 3,582 43 84,509 795
2012 Epi/Obs/Out 2,877 34 146,355 1,107
2012 Pre 360 5 15,136 35
2012 Scr/Det/Dia 1,010 11 36,892 146
2012 Sup/QoL 824 9 13,741 101
2012 The 14,172 213 47,577 474
2012 N/A 1,980 15 46,424 229
2011 Anc/Comp/Cor 4,266 47 90,144 465
2011 Epi/Obs/Out 3,247 34 101,531 658
2011 Pre 395 5 13,273 18
2011 Scr/Det/Dia 1,049 12 34,021 149
2011 Sup/QOL 897 10 12,108 46
2011 The 14,960 217 42,534 449
2011 N/A 108 4 212 0
2010 Anc/Comp/Cor 3,600 40 72,515 578
2010 Epi/Obs/Out 2,946 25 228,234 679
2010 Pre 433 5 21,407 24
2010 Scr/Det/Dia 1,039 11 27,553 151
2010 Sup/QOL 834 9 13,826 80
2010 The 14,722 218 47,703 524
2010 N/A 380 0 7,247 0
FY Total Total of Open Trials Total of Accrued Patients

It is important to note that these are not necessarily unique trials; the same trial may be open at multiple centers.