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RPPR Instructions

 RPPR Instructions

Updated January 26, 2016

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Instructions for the Cancer Center Support Grant
Non-Competing Progress Reports

The purpose of this document is to outline the information required by the Office of Cancer Centers (OCC) and the Office of Grants Administration (OGA) for evaluating a cancer center’s annual progress. All Research Performance Progress Reports (RPPR) forms should be used as relevant. Additional information and resources on the RPPR, including the current RPPR Instruction Guide and training archives, can be found at: http://grants.nih.gov/grants/RPPR/. Please note chapters 6 (Sections A – H) and 7 (Section 7.6) specifically apply to the P30 mechanism. RPPRs and eData files must be submitted two months (60 days) prior to the start of their next budget period.

Budget Complete a budget page for each component requesting CCSG funds. Prior approval by NCI is required to reallocate more than 25% of the funds in any component to other components.
Director’s Overview/6 Essential Characteristics Discuss major accomplishments, changes, updates and any issues noted in previous review that were addressed. Include a copy of Data Table 1.
Administration Discuss changes - if no changes occurred, a narrative is not required.
Senior Leadership Discuss changes - if no changes occurred, a narrative is not required. Provide biosketches and other support as appropriate.
Planning and Evaluation Discuss accomplishments. Provide a list of EAB members and include biosketches for new members.
Developmental Funds Discuss how Developmental Funds were used in the prior year and future plans. Remember that Developmental Funds are restricted – they cannot be reallocated to other components. Inclusion Enrollment Data - if Development Funds were used to support clinical trials, the Center must report inclusion in planned enrollment reports (See RPPR 6.7.G4b 1.).
Research Programs Provide a concise description of accomplishments, changes, and future plans. Attach a list of relevant publications (maximum of 25 to be added in section B2). Major changes to research programs (i.e. deletion, revision, re-organization, re-alignment, etc.) require prior NCI approval and should be reported in detail.
Publications See RRPR 6.3 Section C.1. Include publication resulting from work using CCSG funds (e.g. Developmental Funds,2 CCSG Type 5 Guide Revised January 26, 2016 EPCRS, direct funding support from a shared resource.)
Shared Resources Discuss changes (no publications required) -­‐ if no changes occurred, a narrative is not required. Inclusion Enrollment Data -­‐ if Shared Resource funds were used to support clinical trials, the Center must report inclusion in planned enrollment reports (See RPPR 6.7.G4b 1.).
Clinical Protocol and Data Management Discuss updates and changes - if no changes occurred, a narrative is not required.
Data Safety Monitoring (DSM) Discuss updates and changes - if no changes occurred, a narrative is not required. Major changes (excluding personnel changes) to DSM plan need to be reported to the Office of Cancer Centers (OCC). The revised plan should be submitted to OCC for review and approval.
Human subjects/Inclusion Management System e RPPR 6.G.4
Protocol Review and Monitoring System (PRMS) Discuss updates and changes - if no changes occurred, a narrative is not required. For conditional or disapproved PRMS, discuss efforts to address deficiencies.
Early Phase Clinical Research Support (EPCRS) Discuss accomplishments and future plans. Inclusion Enrollment Data - the Center must report inclusion in planned enrollment reports (See RPPR 6.7.G4b 1.).
Supplements See RPPR 6.B.3. List and summarize all P30 supplements. See RPPR 6.7 Section G1. In the Director’s Overview create a single PDF document that includes all supplements and their corresponding budget page, providing sufficient detail for NCI staff to evaluate progress.
All Personnel Report See RPPR 6.4D & 7.6.D.1
Data Tables Concurrent with submission of the RPPR, submit Data Tables 1-4 as eData to ccsgdata@mail.nih.gov

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